Biorevitalization with polynucleotides
Biorevitalization with PDRN in Miami is a skin-quality treatment in which a topical PDRN serum is applied to the skin immediately after microneedling — not injected. At Activate Beauty in North Miami Beach, it is performed by an Aesthetic Nurse Injector — from $300, beginning with a consultation and carried out under medical supervision.

A topical PDRN serum, applied after microneedling
In this biorevitalization treatment, polynucleotides (PDRN) are used topically. After a controlled microneedling step prepares the skin, the PDRN serum is applied to the surface of the skin — it is not injected. The microneedling is what allows the topical serum to be worked into the freshly prepared skin.
This is a skin-quality approach focused on the condition and appearance of the skin overall. A consultation establishes whether it is appropriate for you and what a sensible plan looks like before anything is carried out.
Consultation first, conservative by design
Our approach is unhurried. We plan around your skin and goals, work conservatively, and never pressure you to proceed.
-
01
Consultation
We review your history and skin, discuss what you are looking for, and confirm whether biorevitalization is appropriate for you. There is no obligation to book a treatment.
-
02
Microneedling step
A controlled microneedling step prepares the skin so that the topical PDRN serum can be worked into the surface afterwards.
-
03
Topical PDRN applied
The PDRN serum is applied topically to the prepared skin. Sessions are usually planned as a short, conservative course rather than a single visit.
-
04
Review
We check in as the course progresses and discuss a maintenance plan over time. Any questions in between are welcome.
Planned around your skin
Biorevitalization with topical PDRN is priced from $300. The plan and number of sessions depend on your skin and goals, which are confirmed at your consultation.
Starting price per session. Your plan depends on what is agreed at your consultation. Individual results vary.
Biorevitalization FAQ
What is biorevitalization with polynucleotides (PDRN)?
It is a skin-quality treatment in which a topical PDRN serum is applied to the skin immediately after microneedling. It is performed by an Aesthetic Nurse Injector, following a consultation and under medical supervision.
Is the PDRN injected?
No. In this treatment the PDRN is used topically — it is applied to the surface of the skin after microneedling, not injected. The microneedling step is what prepares the skin for the topical serum.
Who performs the treatment?
Your treatment is performed by an Aesthetic Nurse Injector at Activate Beauty, under medical supervision. The clinic was founded by Kseniya Zakharova, who brings a decade of hospital patient-care.
How is biorevitalization priced?
Biorevitalization with topical PDRN is priced from $300. The plan and number of sessions depend on your skin and goals, which are confirmed at your consultation. See the pricing page for starting prices across treatments.
Is a consultation required first?
Yes. A consultation is required before a first treatment. We review your history, discuss what you are looking for, and confirm whether the treatment is appropriate for you — with no pressure to proceed.
How many sessions are usual?
Biorevitalization is often planned as a short course of sessions spaced over several weeks, with a maintenance plan discussed afterwards. Your specific plan is agreed at your consultation. Individual results vary.
Other ways we work on skin quality
Considered, conservative, and shaped around yours.
Every course is tailored to the condition of your skin, never a template. Individual results vary; treatment requires consultation.
Plan your biorevitalization consultation.
Reserve a consultation to plan a sensible course for your skin. The treatment is performed under medical supervision — there is no obligation to proceed.